You may opt-out of email communications at any time by clicking on B complex. Some don't work well with prescription medicines. Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. Highly clinically significant. If headaches continue or become severe, tell your doctor promptly. Tell your doctor right away if you have any serious side effects, including: fainting, fast/irregular/pounding heartbeat. Copyright 2023 IBM Watson Health. If concomitant therapy cannot be avoided, monitor clinical effects of the . All rights reserved. What special precautions should I follow? Isosorbide mononitrate helps to prevent angina chest pain from developing. It also may keep some medicines from working as well as they should, such as: If your health care provider tells you it's OK to use an herbal supplement along with medicine, be careful. Isosorbide-5-mononitrate ISMN usually begins acting within 30 minutes and its effects last six to eight hours. If this worries you, talk to your doctor or pharmacist about other options. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. If we combine this information with your protected If you notice any other effects, check with your healthcare professional. May also be prescribed off label for Esophageal Spasm. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. This is a condition where the heart does not beat as efficiently as it should. Anti-ischemic and anti-anginal effects of controlled-release and conventional isosorbide-5-mononitrate in stable angina pectoris. Nitrates in the management of acute coronary syndrome. Headache, dizziness, lightheadedness, nausea, and flushing may occur as your body adjusts to this medication. Follow directions about how much medicine to take. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking isosorbide. Do not try to change the times or the way that you take isosorbide in order to avoid headaches because then the medication may not work as well. You can develop a tolerance to isosorbide mononitrate (Monoket) over time, which means the dose you've been taking doesn't work as well. information is beneficial, we may combine your email and website usage information with GoodRx works to make its website accessible to all, including those with disabilities. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). Usually avoid combinations; use it only under special circumstances. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. Isosorbide mononitrate (Monoket) is a nitrate vasodilator. St. John's wort. Properly discard this product when it is expired or no longer needed. If you notice any other effects, check with your healthcare professional.Call your doctor for medical advice about side effects. Get emergency help immediately if any of the following symptoms of overdose occur: bulging soft spot on the head of an infant, change in the ability to see colors, especially blue or yellow, feeling of constant movement of self or surroundings. If you are having difficulty accessing this website, please call or email us at (855) 268-2822 or ada@goodrx.com so that we can provide you with the services you require through alternative means. Nitrates (eg, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin). Seek alternatives to the CYP3A4 substrate when possible. All rights reserved. A randomized, double-blind, cross-over study. Some of these interactions can be life-threatening. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Accessed Sept. 7, 2022. Isosorbide mononitrate: effectiveness, side effects, alternatives Isosorbide mononitrate is used to prevent chest pain in patients with a certain heart condition (coronary artery disease).This medication belongs to a class of drugs known as nitrates. Accessed Sept. 7, 2022. 7 disease interactions. Isosorbide mononitrate systemic 60 mg (A ID). Take care, thanks. Commonly reported side effects include: See also: isosorbide mononitrate side effects in more detail. Does Viagra add to the risks of melanoma? Although not all of these side effects may occur, if they do occur they may need medical attention. For details see our conditions. Swallow the extended-release tablets or capsules whole; do not crush, chew, or divide them. privacy practices. Be sure to talk to your health care provider before you take any herbal supplements if you take prescription medicines. May also be prescribed off label for Esophageal Spasm. Unable to load your collection due to an error, Unable to load your delegates due to an error. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. Portions of this document last updated: Feb. 01, 2023. We asked 34 people what they think about isosorbide mononitrate (Monoket): Get Isosorbide mononitrate (Monoket) for as low as $29.86, 180 tablets of isosorbide mononitrate 10mg. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Isosorbide Mononitrate (Oral Route) - Mayo Clinic Cardizem may also be used for purposes not listed in this medication guide. [2] Natural Medicines. Your doctor may tell you to take a pain reliever to treat your headaches. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. See also: nitroglycerin side effects in more detail. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. If you become pregnant while taking isosorbide, call your doctor. In: Current Medical Diagnosis & Treatment 2022. These side effects may go away during treatment as your body adjusts to the medicine. Natural Medicines. you should know that you may experience headaches every day during your treatment with isosorbide. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Keep this medication in the container it came in, tightly closed, and out of reach of children. Higher dosages are associated with stomach irritation and Accessed Sept. 7, 2022. Take the missed dose as soon as you remember it. https://naturalmedicines.therapeuticresearch.com. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. It does not work fast enough to relieve the pain of an angina attack that has already started. Do not change the dosing times unless directed by your doctor. It works more slowly and lasts for about 12 hours, so you only need to take it once a day. Our clinical information meets the standards set by the NHS in their Standard for Creating Health Content guidance. You can take your doses either before or after meals. Elantan, Imdur, Isotard, Monomax, Tardisc, Xismox. All rights reserved. Your doctor will tell you which is the right dose for you, and this will also be printed on the label of the pack to remind you about what the doctor said to you. If it is within 2 hours of the next dose, skip the missed dose. What is the difference between the immediate-release (IR) and extended-release (ER) versions of isosorbide mononitrate (Monoket)? 2023 eHealthMe.com. It is best not to drink alcohol while you are on isosorbide mononitrate. What should I know about storage and disposal of this medication? Along with its needed effects, a medicine may cause some unwanted effects. Isosorbide mononitrate 30% immediate-release 70% sustained-release formulation: a review. Lyrica and Metoclopramide drug interaction, Calcitriol and Metoclopramide drug interaction. Does Alcohol Raise Your Blood Pressure? (2) One in 3 patients never experienced headache from the given dosages. Background: Imdur (isosorbide mononitrate) Extended Release and Isordil (isosorbide dinitrate) are vasodilators indicated for the prevention of angina pectoris due to coronary artery disease.. Side effects of Imdur and Isordil that are similar include headache and dizziness.. Side effects of Isordil that are different from Imdur include weakness and skin changes such as redness, tingling, or warmth. Truven Health and GoodRx make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Talk to your provider if you notice your chest pain starts to get worse. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. It works by relaxing and widening blood vessels so blood can flow more easily to the heart.This medication will not relieve chest pain once it occurs. You can consult me online for homeopathic treatment. Modified-release nitrate preparations: use a once-daily dose to maintain a nitrate-low period and thus minimize tolerance. (3) The overall number of headache attacks in the first period of active treatment was significantly higher than in the second period irrespective of the dosages given. government site. Otherwise, call a poison control center right away. See also: aspirin side effects in more detail. Does Isosorbide Mononitrate interact with other drugs you are taking? Mayo Clinic; 2021. All rights reserved. 2021 May 11;39:28. doi: 10.11604/pamj.2021.39.28.22180. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. Isosorbide tablets are also used with other medications to treat heart failure. Isosorbide mononitrate: isosorbide mononitrate. Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). List of Antianginal agents (antianginal drugs) - Drugs.com Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Isosorbide mononitrate (Monoket) can cause some serious health issues. Tell your doctor if this medication stops working well (for example, you have more frequent or worsening chest pain). Saw palmetto. Clipboard, Search History, and several other advanced features are temporarily unavailable. It is used to treat and prevent a wide range of different conditions. The most common side-effect is headache. Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction. Isosorbide mononitrate is very similar to isosorbide dinitrate. We don't support your browser. Use this medication regularly to get the most benefit from it. If you do not remember until your next dose is nearly due, then leave out the forgotten dose and take your next dose when it is due. Epub 2006 Mar 22. Bethesda, MD 20894, Web Policies Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Also, it is not intended to be taken just before physical activities (such as exercise or sexual intercourse) to prevent chest pain. Yet significantly fewer patients had headache on low dosage than on high dosage (45 vs 57, P < 0.02). Older adults may be more sensitive to the side effects of this medication, especially dizziness and lightheadedness, which could increase the risk of falls. Melanoma is one of the most dangerous forms of skin cancer which develops in the skin cells that produce melanin ( the pigment that gives your skin its color). Synthroid (levothyroxine) Tylenol (acetaminophen) Vitamin B12 (cyanocobalamin) Vitamin C (ascorbic acid) Vitamin D3 (cholecalciferol) Isosorbide mononitrate disease interactions There are 7 disease interactions with isosorbide mononitrate which include: AMI anemia hemodialysis hypotension intracranial pressure hypertrophic cardiomyopathy glaucoma Nitroglycerin has an average rating of isosorbide mononitrate prices. What conditions does Isosorbide Mononitrate treat? In a randomized, double-blind, crossover study, 89 patients with stable angina pectoris were studied to compare two different dosage strategies of isosorbide-5-mononitrate (5-ISMN). Natural Medicines. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. Try our Symptom Checker Got any other symptoms? Alcohol or marijuana (cannabis) can make you more dizzy. Other side effects not listed may also occur in some patients. Use of herbal products and potential interactions in patients with cardiovascular diseases. Drug information provided by: IBM Micromedex. Treatment and prognosis of heart failure with preserved ejection . Isosorbide mononitrate (Monoket) is available as a generic medication and may be significantly cheaper compared to the brand version. This is not a complete list of possible side effects. The use of the Truven Health products is at your sole risk. Natural Medicines. May also be prescribed off label for Esophageal Spasm. Isosorbide - StatPearls - NCBI Bookshelf Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Store at room temperature away from light and moisture. Both versions of isosorbide mononitrate (Monoket) contain the same active ingredient. This medication belongs to a class of drugs known as nitrates. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or to 30 mg 5-ISMN od for one week followed by 60 mg 5-ISMN od for one week. Thirty percent of the patients never experienced headache from the given dosages. Do not drink alcohol while taking View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. FOIA Your doctor will prescribe you a short-acting nitrate for you to take if this happens. Isosorbide mononitrate is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). 19 are major, 174 are moderate, and 2 are minor. The list below does not include all possible drug interactions with isosorbide mononitrate (Monoket). Keep all medicines out of the reach and sight of children. The extended-release tablet usually is taken once daily in the morning. 88 ratings on Drugs.com. This risk may be even higher for certain groups. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Isosorbide mononitrate - UpToDate You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. Isosorbide may not work as well after you have taken it for some time or if you have taken many doses. Isosorbide mononitrate | Drugs | BNF | NICE Unauthorized use of these marks is strictly prohibited. Each day, take the first dose when you wake up, then take the second dose 7 hours later. With any medication, there are risks and benefits. Some of the common derivatives include isosorbide dinitrate and isosorbide mononitrate, which are . American Society of Health-System Pharmacists, Inc. Disclaimer, U.S. Department of Health and Human Services. Do infrared saunas have any health benefits? Truven Health does not assume any responsibility or risk for your use of the Truven Health products. St. Joseph 81 mg Aspirin Enteric Safety-Coated. 8.0 out of 10 from a total of Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. Using this medicine with any of the following medicines is not recommended. This content does not have an Arabic version. Sept. 26, 2022. Isosorbide mononitrate Alternatives Compared - Drugs.com The body tends to develop a tolerance (decreased sensitivity) to ISMN when it is used continuously over 24 hours. Call your doctor for medical advice about side effects. Talk to your doctor about the possible risks of using this medication for your condition. Isosorbide mononitrate dose and side-effects info | Patient Unless there is a specific reason you need the brand, the generic medication will be a better value. Higher than recommend dosage of sublingual isosorbide dinitrate for treating angina pectoris: a case report and review of the literature. Learn to reduce stress through mindful living. Real test is coronary angiography. This should pass after a few days. Isosorbide immediate-release tablets are used for the management of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). About one-half of adults in the United States say they have used one or more supplements in the past 30 days. 2005 - 2023 WebMD LLC. You need to take it every day in order for it to work. You may report side effects to the FDA at 1-800-FDA-1088. The herb licorice may lower warfarin levels and can add to digoxin's effects. Try to keep your regular appointments with your doctor. Even if the medication is working, you may experience some unwanted side effects. Always consult your healthcare provider. We study millions of patients and 5,000 more each day. These products are provided 'AS IS' and 'as available' for use, without warranties of any kind, either express or implied. Duplication for commercial use must be authorized by ASHP. Accessed Sept. 7, 2022. Canada residents can call a provincial poison control center. Tachjian A, et al. Includes Isosorbide Mononitrate indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. Which drugs or supplements interact with isosorbide mononitrate? No, that's not true all the time. This should pass after a few days. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. sharing sensitive information, make sure youre on a federal Do not drive, use machinery, or do anything that needs alertness until you can do it safely. A very serious allergic reaction to this drug is rare. Isosorbide mononitrate, sold under many brand names, is a medication used for heart-related chest pain ( angina ), heart failure and esophageal spasms. Accessed Sept. 7, 2022. Vascular dilatation can precipitate venous pooling with decreased return to the heart, hypotension and reflex tachycardia. Talk to your doctor if you are using marijuana (cannabis). Consult your doctor for more details. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. ** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. Never take extra doses or stop taking it suddenly unless your provider tells you to do so. The drug donates nitric oxide to the body, which is similar to all other Isosorbide mononitrates. Isosorbide dinitrate dose 30-120 mg daily in divided doses. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Can isosorbide mononitrate cause problems? View more, Nitroglycerin dilates veins, relieving chest pain and lowering blood pressure. Do not stop taking isosorbide without talking to your doctor. The short-acting tablet is usually taken as 10 mg to 40 mg by mouth 2 or 3 times daily with at least a 14 hour period of time per day where you don't take any doses. Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. Isosorbide mononitrate (Monoket): Basics, Side Effects & Reviews - GoodRx Cleophas TJ, Niemeyer MG, Zwinderman AH, van der Wall EE. Isosorbide Mononitrate - Uses, Side Effects, Substitutes, Composition coma (loss of consciousness for a period of time). 8600 Rockville Pike 55 ratings on Drugs.com. It might help to take isosorbide mononitrate and dinitrate after meals. An official website of the United States government. Prices for isosorbide mononitrate (Monoket) start at just $29.86 with a GoodRx coupon. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Herbal medications in cardiovascular medicine. Isosorbide mononitrate helps to prevent angina chest pain from developing. Disclaimer. Of the total drug interactions, It is components of vit. Natural Medicines. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Let your provider know if you are using any medications for erectile dysfunction before you start taking isosorbide mononitrate (Monoket). Click here for an email preview. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). What are the interactions of Isosorbide Mononitrate ? Would you like email updates of new search results? To use the sharing features on this page, please enable JavaScript. The extended-release capsule usually is taken once daily. Elsevier; 2021. https://www.clinicalkey.com. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. However, you should not flush this medication down the toilet. Angina pain develops if part of your heart muscle does not get as much blood and oxygen as it needs. Isosorbide is a medication used to treat and prevent angina pectoris in patients with coronary heart disease. Isosorbide mononitrate (Monoket) is not a medication you take if you think you are having a heart attack. This site complies with the HONcode standard for trustworthy health information: verify here. Overview of herbal medicines and dietary supplements. Things to remember when you fill your prescription. Licorice. This drug may make you dizzy. Good at preventing chest pain caused by heart disease, Available as a generic version, making it less expensive, Long-acting version only needs to be taken once daily, Short-acting tablets have to be taken on a very specific schedule for the medication to work best. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. It does not have such side effects. This medicine is available only with your doctor's . Careers. This does not necessarily mean no interactions exist. Isosorbide Mononitrate - Medicine.com Isosorbide mononitrate - Wikipedia Advertising revenue supports our not-for-profit mission. It might help to keep the room cool and use a fan. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Is isosorbide mononitrate (Monoket) the same as nitroglycerin (Nitrostat)? If any of these effects persist or worsen, tell your doctor or pharmacist promptly. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. Headache is often a sign that this medication is working. Isosorbide mononitrate belongs to the group of medicines called nitrates. A single copy of these materials may be reprinted for noncommercial personal use only. Isosorbide mononitrate dose 10 mg twice daily to 120 mg daily in divided doses. My EKG showed Assess your symptoms online with our free symptom checker. Some products have ingredients that could worsen your heart failure. It will not treat an angina attack that has already begun. Background: Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. Bauer B (expert opinion). In the US - Call your doctor for medical advice about side effects. Cardizem Alternatives Compared - Drugs.com What are the side effects of Isosorbide Mononitrate ? Now, youll enjoy a streamlined experience created specifically for healthcare providers. Diabetes treatment: Can cinnamon lower blood sugar? A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. information and will only use or disclose that information as set forth in our notice of In case of overdose, call the poison control helpline at 1-800-222-1222. The extended-release tablet usually is taken once daily in the morning. These headaches may be a sign that the medication is working as it should. Methods: Important information about all medicines, Notes on Isosorbide mononitrate dose and side-effects info, https://patient.info/medicine/isosorbide-mononitrate-elantan-imdur-isotard-monomax-tardisc-xismox, Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets, Carmil XL; Chemydur XL; Elantan LA; Imdur; Isib XL; Ismo; Isodur XL; Isotard XL; Modisal XL; Monomax SR; Monomil XL; Nyzamac SR; Relosorb XL; Tardisc XL; Trangina XL; Xismox XL; Zemon XL, Tablets, modified-release (longer-acting) tablets, and modified-release (longer-acting) capsules, Ask your doctor or pharmacist to recommend a suitable painkiller. Information is also available online at https://www.poisonhelp.org/help. Is it safe to drive while on this medicine? Along with its needed effects, a medicine may cause some unwanted effects. If you have been told by a doctor you have low levels of iron in your blood (anaemia), or low levels of oxygen in your blood (hypoxaemia). Take extra precautions to avoid falling during your treatment with isosorbide. Isosorbide Mononitrate - Uses, Side Effects, and More - WebMD Federal government websites often end in .gov or .mil. All Rights Reserved. Isosorbide can only be used to prevent angina; it cannot be used to treat an episode of angina once it has begun. Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx. Check with your doctor immediately if any of the following side effects occur: burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, fast, slow, irregular, pounding, or racing heartbeat or pulse, itching, pain, redness, or swelling on the leg, numbness or tingling in the hands, feet, or lips, pain or discomfort in the arms, jaw, back, or neck, pain, tension, and weakness upon walking that subsides during periods of rest, shakiness in the legs, arms, hands, or feet, swelling of the face, fingers, feet, or lower legs, trembling or shaking of the hands or feet, vomiting of blood or material that looks like coffee grounds, Bluish-colored lips, fingernails, or palms.